Buy 2F-Ketamine Crystal Powder Online | High-Purity Fluorinated Arylcyclohexylamine Research Chemical

Introduction to Buy 2F-Ketamine Crystal Powder

Buy 2F-Ketamine Crystal Powder (2-Fluorodeschloroketamine / 2-FDCK), designated in pharmacological literature as a novel synthetic arylcyclohexylamine, is a highly potent research chemical and a critical reference standard in neuropharmacological and forensic research. Structurally, it is the 2-fluoro analog of Ketamine, featuring a fluorine atom at the 2-position of the phenyl ring in place of the chlorine atom, while retaining the characteristic 2-oxo (ketone) group and the methylamine chain.

In neuropharmacological research, the introduction of a fluorine atom at the 2-position is a paramount structural modification. The 2-fluoro group fundamentally alters the molecule’s pharmacokinetic profile by blocking hepatic hydroxylation at the 2-position—a primary metabolic pathway for Ketamine. This “metabolic shielding” drastically increases bioavailability and extends the duration of NMDA receptor occupancy. 2F-Ketamine functions as a potent non-competitive NMDA receptor antagonist, binding to the PCP site within the NMDA receptor complex and blocking glutamate-gated ion channels. Unlike many arylcyclohexylamines supplied as unstable, hygroscopic freebase oils that are virtually impossible to accurately weigh, or as micro-fine dusts prone to dangerous static cling, our 2F-Ketamine is supplied as a stable crystalline hydrochloride (HCl) powder. This crystal format ensures exceptional physical stability, precise measurability, and drastically reduces electrostatic handling hazards. Note: This product is strictly intended for in-vitro research and analytical purposes only.

Key Features and Benefits – Buy 2F-Ketamine Crystal Powder

• Crystalline Stability: The HCl salt crystalline structure prevents the compound from melting into an unmanageable, viscous oil at room temperature—a notorious issue with freebase arylcyclohexylamines—ensuring accurate, reproducible micro-weighing.
• Reduced Static Hazard: Unlike ultra-fine dissociative powders that are highly prone to static cling and dangerous aerial dispersion, the crystal/powder format is significantly safer and easier to handle within laboratory environments.
• Raw Powder Versatility: Supplied as a pure, crystalline powder, this format allows researchers to create precise, custom-concentration volumetric solutions tailored to unique in-vitro assay requirements, eliminating the variables of pre-mixed liquids or fixed-dose units.
• Fluorinated SAR Mapping: 2F-Ketamine provides researchers with the essential 2-fluoro analog required for comparative structural-activity relationship (SAR) studies against 2-chloro (Ketamine) and 2-deschloro (DCK) arylcyclohexylamines, mapping how 2-position halogenation dictates NMDA receptor affinity and metabolic clearance.
• Metabolic Shielding Research: Essential for modeling how 2-fluoro substitution blocks enzymatic norketamine hydroxylation, altering bioavailability and extending the half-life of arylcyclohexylamines in hepatocyte models.
• Analytical Standard: Foremost reference standard for forensic laboratories requiring pure, verified materials to validate LC/MS and GC/MS instruments and detect emerging fluorinated NPS in biological matrices.

Product Specifications

• Chemical Name: 2-(2-Fluorophenyl)-2-(methylamino)cyclohexan-1-one hydrochloride
• Common Designation: 2F-Ketamine / 2-FDCK / 2-Fluorodeschloroketamine
• CAS Number: 1195130-91-8 (Freebase)
• Class: Arylcyclohexylamine / Fluorinated NMDA Antagonist / Research Chemical
• Form: Crystalline Powder (Hydrochloride Salt)
• Purity: ≥ 98% (Verified by Independent Third-Party Testing)
• Appearance: White to off-white crystalline powder
• Storage Requirements: Store in a cool, dry, dark environment (ideally -20°C for long-term archival). Keep container tightly sealed under inert gas to prevent hygroscopic absorption and oxidation.
• Solubility: Freely soluble in water, DMSO, and ethanol.

Applications and Usage

2F-Ketamine Crystal Powder is exclusively designated for in-vitro (outside a living organism) research and analytical applications. Common laboratory applications include:

• NMDA Receptor Binding Assays: Investigating the compound’s affinity and efficacy as a non-competitive antagonist at the PCP binding site on the NMDA receptor using isolated neuronal membrane preparations.
• Fluorinated vs. Chlorinated SAR Studies: Contrasting the pharmacokinetic properties and receptor conformational changes induced by 2-fluoro substitution (2F-Ketamine) versus 2-chloro (Ketamine) to map the steric and electronic limits of the receptor binding pocket.
• Metabolic Pathway Studies: Analyzing the hepatic breakdown of fluorinated arylcyclohexylamines using hepatocyte cultures and liver microsomes, specifically quantifying the reduction in 2-hydroxylation and the shift to alternative metabolic routes (e.g., N-demethylation).
• Forensic and Analytical Calibration: Utilizing the precisely characterized crystal powder as a certified reference material (CRM) for GC/MS, LC/MS, and NMR spectroscopy to validate analytical instruments and detect 2F-Ketamine and its unique fluorinated biomarkers in biological matrices.

Disclaimer: This product is not for human or veterinary consumption. It must only be handled in controlled laboratory environments by qualified professionals.

Purity and Testing

We guarantee a purity level of ≥ 98% for our 2F-Ketamine Crystal Powder. Every batch undergoes rigorous, independent third-party testing to verify chemical identity, absolute purity, and the absence of dangerous residual solvents, heavy metals, or unreacted precursors. Because arylcyclohexylamines are highly prone to degradation and are a heavily counterfeited class, we perform exhaustive screening to ensure the absolute absence of dangerous contaminants (such as Ketamine, DCK, MXE, or synthetic opioids). Certificates of Analysis (CoA) and Safety Data Sheets (SDS) are provided upon request.

Safety and Handling

WARNING: 2F-KETAMINE IS A HIGHLY POTENT NMDA ANTAGONIST AND CENTRAL NERVOUS SYSTEM DEPRESSANT. EXTREME CAUTION IS REQUIRED.

• Personal Protective Equipment (PPE): Must wear nitrile gloves, chemical-resistant safety goggles, and a P100 particulate respirator when weighing or transferring the powder.
• Ventilation: Handling must only occur within a certified chemical fume hood to prevent the inhalation of aerosolized particles.
• Accidental Exposure: In the event of skin contact, wash the area thoroughly with soap and water. For eye contact, flush with copious amounts of water for at least 15 minutes.
• Hygiene: Remove contaminated clothing immediately and wash hands thoroughly after handling, even when PPE is utilized.
• Secure Storage: Keep powder locked away in a secure, access-controlled laboratory cabinet, out of reach of unauthorized personnel.

Global Shipping and Discreet Delivery

• Global Reach: We ship 2F-Ketamine Crystal Powder internationally, in strict compliance with international shipping regulations.
• Discreet Packaging: All orders are dispatched in unmarked, tamper-evident, and odor-proof packaging. The outer packaging does not indicate the nature of the contents.
• Rapid Processing: Orders are processed and shipped within 24 hours of cleared payment. We offer standard and express courier options with full end-to-end tracking.
• Secure Handling: Powders are double-sealed in moisture-barrier bags and placed within sturdy outer containers to prevent damage during transit.

Why Choose Us To Buy 2F-Ketamine Crystal Powder?

• Uncompromising Quality: We work directly with top-tier chemical synthesis laboratories and verify every batch in-house and via third-party labs before it reaches you.
• Total Transparency: We provide full analytical data. What is on the label is exactly what is in the bag—no fillers, no impurities, no compromises.
• Expert Customer Support: Our support team understands the nuances of research chemicals and is ready to assist with CoA requests, shipping inquiries, and technical questions.
• Secure Transactions: We utilize SSL encryption and accept secure, discreet payment methods, including major cryptocurrencies (Bitcoin, Monero, Ethereum) and secure bank transfers.

Legal and Safety Compliance

2F-Ketamine Crystal Powder is sold strictly as a research chemical and is not approved by the FDA, EMA, or any equivalent regulatory body for human or veterinary use.

It is the sole responsibility of the purchaser to ensure that the acquisition, possession, and use of 2-Fluorodeschloroketamine comply with all local, state, national, and international laws. Warning: 2F-Ketamine is a potent central nervous system depressant and NMDA antagonist. Ingestion can cause severe, life-threatening psychological and physiological effects, including profound dissociation, respiratory depression, and severe psychological distress. As a direct analog of Ketamine (a Schedule III controlled substance in many jurisdictions), it frequently falls under federal analogue acts or specific NPS legislation globally. We do not ship to regions where this compound is explicitly prohibited. By purchasing from us, you affirm that you are a qualified researcher or institutional buyer over the age of 18, and you assume all legal liability for the product upon delivery.

Frequently Asked Questions (FAQ)

Q1: What is 2F-Ketamine?
A: 2F-Ketamine (2-Fluorodeschloroketamine) is a novel synthetic arylcyclohexylamine. It is the 2-fluoro analog of Ketamine, featuring a fluorine atom where Ketamine has a chlorine. It acts primarily as a potent non-competitive NMDA receptor antagonist (dissociative), blocking the glutamate-gated ion channels in vitro.

Q2: What makes 2F-Ketamine different from Ketamine?
A: The primary difference is the halogen at the 2-position of the phenyl ring. Ketamine has a 2-chloro group, while 2F-Ketamine features a 2-fluoro group. The fluorine atom significantly increases lipophilicity and blocks hepatic 2-hydroxylation (metabolic shielding), altering metabolic stability and duration of action, making it essential for comparative fluorinated SAR research.

Q3: Why choose the crystal powder form over freebase?
A: Freebase arylcyclohexylamines are notoriously unstable, often melting into an unmanageable, sticky oil at room temperature, making accurate weighing impossible. The crystalline HCl powder form is stable, solid, and dry, allowing for precise micro-weighing and reproducible assay preparation. It also generates less airborne dust than micro-fine pulverized powders, reducing static cling hazards.

Q4: Can 2F-Ketamine Crystal Powder be consumed?
A: Absolutely not. 2F-Ketamine is a potent NMDA antagonist and CNS depressant. It is sold strictly for in-vitro laboratory and analytical research. Ingestion can cause unpredictable, severe psychological and cardiovascular effects and is strictly prohibited.

Q5: Do you provide a Certificate of Analysis (CoA)?
A: Yes. We provide a comprehensive CoA—including HPLC, GC/MS, and NMR data—for every batch we sell. This guarantees the identity, purity, and mass of the compound.

Q6: Is it legal to buy 2F-Ketamine in my country?
A: Legality varies drastically by country and is subject to change. Because it is a direct structural analog of Ketamine, it is often controlled under analogue acts or specific NPS bans. We cannot provide legal advice. It is your responsibility to research your local laws regarding this compound before placing an order.

Q7: How should I store 2F-Ketamine Crystal Powder for long-term research?
A: For maximum longevity, store 2F-Ketamine powder in an airtight, amber glass vial under an inert gas (like Argon) in a freezer set to -20°C. Keep away from direct sunlight, heat, and moisture.